Thiamine Supplementation

An infant wearing a pink shirt being examined by a doctor with a stethoscope

Childhood Thiamine Supplementation Research 

UO Research Shows Vitamin B1 Supplements Prevent Childhood Beriberi and Boost Development

University of Oregon Psychology Professors Dare Baldwin and Jeffery Measelle are part of a long-term project to study how thiamine (vitamin B1) supplementation and fortification can reduce beriberi in children. Beriberi is a disease caused by a deficiency in vitamin B1 (thiamine). The disease has a heightened incidence in places where people primarily eat nutrient poor foods such as white rice as a primary food staple.  Lack of thiamine is known to cause developmental delays in cognitive, motor, and language development across the first years for children. Measelle, Baldwin, and their team have found that adding Thiamine to pregnant and breastfeeding mothers can reduce the likelihood of nutritional stunting and beriberi disease in babies – which has positive, long lasting neurocognitive developmental and community outcomes.  

Researchers

jeff Measelle

Jeffrey Measelle, Professor
Co-Director, Developmental Social Biology Lab

Affiliate, Global Health Program  Developmental Stress Biology, Caregiving Support for Early Brain Development, Pediatric Global Health
Developmental Social Biology Lab

Dare Baldwin Headshot

Dare Baldwin, Professor
Psychology

Development, Language Acquisition, Event Processing, Cognitive and Social-Cognitive Development, Developmental Consequences of Malnutrition, Behavioral Response to Natural Hazards

Manual breast pump and bottle with breast milk on the background of mother holding in her hands and breastfeeding baby
Research in Cambodia found that giving breastfeeding mothers a daily 1.2 mg thiamine supplement was enough to achieve healthy breast milk thiamine levels, potentially preventing infant beriberi in regions where this deficiency is common.
Mother breastfeeding her newborn baby beside window
Study reveals that high-dose vitamin B1 supplements given to nursing mothers can boost infant language development, but the benefits may fade without continued nutritional support beyond 6 months.
Chalkboard with the chemical formula of vitamin B1
Research shows giving breastfeeding mothers vitamin B1 supplements boosts infant language development in rice-dependent communities.